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Patterns of Nonfatal Heroin Overdose Over a 3-Year Period: Findings From the Australian Treatment Outcome Study

机译:三年中非致命海洛因过量的模式:澳大利亚治疗结果研究的发现

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摘要

To determine annual patterns and correlates of nonfatal heroin overdose across 3 years, data were analyzed on 387 heroin users recruited for the Australian Treatment Outcome Study (ATOS), interviewed at 12, 24, and 36 months. A heroin overdose across follow-up was reported by 18.6%, and naloxone had been administered to 11.9%. Annual rates of overdose declined between baseline and 12 months and then remained stable. Previous overdose experience was strongly related to subsequent overdose. Those with a history of overdose before ATOS were significantly more likely to overdose during the study period. In particular, there was a strong association between overdose experience in any 1 year and increased overdose risk in the subsequent year. This is the first study to examine long-term annual trends in nonfatal heroin overdose. While overdose rates declined after extensive treatment, substantial proportions continued to overdose in each year, and this was strongly associated with overdose history.
机译:为了确定3年中非致命海洛因过量的年度模式和相关性,对12个月,24个月和36个月接受澳大利亚治疗结果研究(ATOS)招募的387名海洛因使用者进行了数据分析。据报道,随访期间海洛因用药过量为18.6%,纳洛酮的使用率为11.9%。在基线和12个月之间,过量用药的年率下降,然后保持稳定。先前的过量用药经验与随后的过量用药密切相关。那些在ATOS之前有过用药史的人在研究期间用药过量的可能性要大得多。特别是,任何一年的服药过量经验与随后一年的服药过量风险增加之间都有很强的联系。这是第一个研究非致命海洛因过量长期长期趋势的研究。广泛治疗后,尽管服药过量率下降,但每年仍有相当一部分继续服药过量,这与服药过量史密切相关。

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